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Calcium citrate also a relatively low solubility (~15 mM in the cold), and its solubility decreases as the temperature goes up.  Thus, getting calcium citrate crystals is a possibility if both components are at a relatively high concentration.  However, sodium citrate alone is soluble up to ~1.4 M at least, depending on the pH.
 
Calcium citrate also a relatively low solubility (~15 mM in the cold), and its solubility decreases as the temperature goes up.  Thus, getting calcium citrate crystals is a possibility if both components are at a relatively high concentration.  However, sodium citrate alone is soluble up to ~1.4 M at least, depending on the pH.
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==What if I have a membrane protein?==
 
Most nonionic detergents do not form crystals in aqueous solution.  Check the published phase diagrams to be sure.  In fact, few of the alkyl glycoside detergents (like octyl glucoside and dodecyl maltoside) crystallize if the sugar group is a beta anomer, even in organic solvents.  This is one of the reasons why they are so difficult to purify by recrystallization.  Under some extreme conditions, nonionic detergents can form liquid crystals, but these are rare.
 
Most nonionic detergents do not form crystals in aqueous solution.  Check the published phase diagrams to be sure.  In fact, few of the alkyl glycoside detergents (like octyl glucoside and dodecyl maltoside) crystallize if the sugar group is a beta anomer, even in organic solvents.  This is one of the reasons why they are so difficult to purify by recrystallization.  Under some extreme conditions, nonionic detergents can form liquid crystals, but these are rare.
  
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