https://wiki.uni-konstanz.de/ccp4/index.php?title=Solvent_content&feed=atom&action=history Solvent content - Revision history 2024-03-29T10:37:05Z Revision history for this page on the wiki MediaWiki 1.39.6 https://wiki.uni-konstanz.de/ccp4/index.php?title=Solvent_content&diff=2100&oldid=prev Kay: Created page with "Solvent content can be calculated with the CCP4 program matthews_coef, or with a [http://www.ruppweb.org/Mattprob/ Web server]. Usual values are around 50%, but the range is f..." 2012-03-13T07:36:32Z <p>Created page with &quot;Solvent content can be calculated with the CCP4 program matthews_coef, or with a [http://www.ruppweb.org/Mattprob/ Web server]. Usual values are around 50%, but the range is f...&quot;</p> <p><b>New page</b></p><div>Solvent content can be calculated with the CCP4 program matthews_coef, or with a [http://www.ruppweb.org/Mattprob/ Web server]. Usual values are around 50%, but the range is from about 30% to 85%. Crystals with low solvent content usually diffract better than those with high solvent content.<br /> <br /> For pencil-and-paper calculations: The average volume of an amino acid is 140 A**3 ([https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ccp4bb;adc1f32e.1203]), that of a nucleotide 380 A**3 ([https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ccp4bb;e196902d.1203]).<br /> <br /> Protein and nucleic acids have different partial specific volumes (0.74 cm3/g &#039;&#039;versus&#039;&#039; 0.50 cm3/g).</div> Kay