Protein Crystallography and Molecular Bioinformatics
University of Konstanz

Publications

Publications

  1. Diederichs, K., Welte, W., Kreutz, W.(1985)
    2. Determination of interaction forces between higher plant thylakoids and electron-density-profile evaluation using small-angle X-ray scattering.
    Biochim. Biophys. Acta 809, 107-116

  2. Welte, W., Leonhard, M., Diederichs, K.,Weltzien, H.U., Restall, C., Hall, C., Chapman, D. (1989)
    3. Stabilization of detergent solubilized Ca++-ATPase by polyethyleneglycol.
    Biochim. Biophys. Acta 984, 193-199

    1990

  3. Diederichs, K., Schulz, G.E. (1990)
    4. Three-dimensional structure of the complex between the mitochondrial matrix adenylate kinase and its substrate AMP.
    Biochemistry 29, 8138-8144

  4. Schulz, G.E., Müller, C.W., Diederichs, K. (1990)
    5. Induced-fit movements in adenylate kinases.
    J. Mol. Biol. 213, 627-630

    1991

  5. Diederichs, K., Schulz, G.E. (1991)
    6. The refined structure of the complex between adenylate kinase from beef heart mitochondrial matrix and its substrate AMP at 1.85Å resolution.
    J. Mol. Biol. 217, 541-549

  6. Diederichs, K., Jacques, S., Boone, T., Karplus, P.A. (1991)
    7. Low-resolution structure of recombinant human Granulocyte-Macrophage Colony Stimulating Factor.
    J. Mol. Biol. 221, 55-60

  7. Diederichs, K., Boone, T., Karplus, P.A. (1991)
    8. Novel fold and putative receptor binding site of Granulocyte-Macrophage Colony-Stimulating Factor.
    Science 254, 1779-1782

    1993

  8. Forst, D., Schülein, K., Wacker, T., Diederichs, K., Kreutz, W., Benz, R., Welte, W. (1993)
    9. Crystallization and Preliminary X-ray Diffraction Analysis of ScrY, a Specific Bacterial Outer Membrane Porin.
    J. Mol. Biol. 229, 258-262

    1994

  9. Diederichs, K. (1994)
    10. SUPERIMPOSE - a program for the unambiguous structural superposition of spatially related molecules, including macromolecules.
    J. Appl. Cryst. 27, 436

  10. Diederichs, K. (1994)
    11. A comparison of some heavy-atom refinement and phasing programs.
    In: Joint CCP4 and ESF-EACBM Newsletters on Protein Crystallography (Bailey, S. and Wilson, K., eds.) 31, 23-30

  11. Welte, W., Nestel, U., Wacker, T., Diederichs, K. (1994)
    12. Structure and Function of the Porin Channel.
    Kidney International 48, 930-940

    1995

  12. Diederichs, K., Wacker, T., Hauk, J., Kreutz, W., Welte, W. (1995)
    13. Molecular and Crystal Structure of an Amphiphile: 4'-Propoxybiphenyl-4-methyl-N,N-dimethylamineoxide.
    Biochim. Biophys. Acta 1234, 244-248

  13. Diederichs, K. (1995)
    14. Structural Superposition of Proteins with Unknown Alignment and Detection of Topological Similarity using a Six-dimensional Search Algorithm.
    Proteins: Structure, Function, and Genetics 23, 187-195

  14. Hirsch, A., Wacker, T., Weckesser, J., Diederichs, K., Welte, W. (1995)
    15. Purification, Characterization, Crystallization and Preliminary X-Ray Results from Paracoccus denitrificans Porin.
    Proteins: Structure, Function, and Genetics 23, 282-284

  15. Bisig, D.A., Di Iorio, E.E., Diederichs, K., Winterhalter, K.H.,, Piontek, K. (1995)
    16. Crystal Structure of Asian Elephant (Elephas maximus) Cyano-Metmyoglobin at 1.78 Å Resolution.
    J. Biol. Chem. 270, 20754-20762

    1996

  16. Przybylski, M., Glocker, M.O., Nestel, U., Schnaible, V., Diederichs, K., Weckesser, J., Schad, M., Schmid, A., Welte, W., Benz, R. (1996)
    17. X-Ray Crystallographic and Mass Spectrometric Structure Determination and Functional Characterisation of Succinylated Porin from Rhodobacter capsulatus: Implications for Ion Selectivity and Single-Channel Conductance.
    Protein Science 5,1477-1489

  17. Brizzolara, D., Cantow, H.-J., Diederichs, K., Keller, E., Domb, A.J. (1996)
    18. Mechanism of the Stereocomplex Formation between Enantiomeric Poly(lactide)s.
    Macromolecules 29, 191-197

  18. Hofmann, E., Wrench, P.M., Sharples, F.P., Hiller, R.G., Welte, W., Diederichs, K. (1996)
    19. Structural basis of light harvesting by carotenoids: peridinin-chlorophyll-protein from Amphidinium carterae.
    Science 272, 1788-1791

  19. Rozwarski, D.A., Diederichs, K., Hecht, T., Boone, T., Karplus, P.A. (1996)
    20. Refined Crystal Structure and Mutagenesis of Human Granulocyte-Macrophage Colony Stimulating Factor.
    Proteins: Structure, Function, and Genetics 26, 304-313

    1997

  20. Ritter, S., Hiller, R.G., Wrench, P.M., Wacker, T., Welte, W., Diederichs, K. (1997)
    21. Purification, Crystallization and preliminary x-ray analysis of a phycourobilin-containing phycoerythrin.
    Protein and Peptide Letters 4, 69-74

  21. Ritter, S., Frey, I., Diederichs, K., Grathwohl, D., Keul, J., Baumstark, M.W. (1997)
    22. Crystallization and preliminary x-ray diffraction data of two different low density lipoprotein (LDL) subfractions.
    Proteins: Structure, Function, and Genetics 28, 293-297

  22. Hirsch, A., Breed, J., Saxena, K., Richter, O.-M.H., Ludwig, B., Diederichs, K., Welte, W. (1997)
    23. The structure of porin from Paracoccus denitrificans at 3.1Å resolution.
    FEBS Letters 404, 208-210

  23. Diederichs, K., Karplus, P.A. (1997)
    24. Improved R-factors for Diffraction Data Analysis in Macromolecular Crystallography.
    Nature Structural Biology 4, 269-275

  24. Srikumar, R., Dahan, D., Arhin, F.F., Tawa, P., Diederichs, K., Coulton, J.W. (1997)
    25. Porins of Haemophilus influenzae type b mutated in loop 3 and in loop 4.
    J. Biol. Chem. 272, 13614-13621

  25. Hofmann, E., Hiller, R.G., Welte W. and Diederichs, K. (1997)
    26. Light Harvesting by Carotenoids: Peridinin-Chlorophyll-Protein (PCP) from Amphidinium Carterae - Structural Relation to Proteins with Globin Fold.
    Zeitschrift für Kristallographie 11 (Supplement), XXX

    1998

  26. Zeth, K., Schnaible, V., Przybylski, M., Welte, W., Diederichs, K., Engelhardt, H. (1998)
    27. Crystallization and mass spectrometric analysis of native and chemically modified porin Omp32 from Comamonas acidovorans.
    Acta Cryst D54, 650-653

  27. Diederichs, K., Hofmann, E. (1998)
    28. Structural relation of peridinin-chlorophyll a-protein (PCP) and proteins with globin-like fold. A testable hypothesis for its folding and assembly pathway.
    In: Proceedings of the NATO Advanced workshop "New Methods for the Study of Molecular Aggregates", (Standing, K. and Ens, W., Eds.), pp. 277-284. Kluwer Academic Publishers, Dordrecht, Niederlande

  28. Welte, W., Diederichs, K., Przybylski, M., Glocker, M., Benz, R., Breed, J. (1998)
    29. X-ray crystallographic and mass spectrometric structure determination and functional characterization of succinylated porin from R. capsulatus : Implications for ion selectivity and single-channel conductance.
    In: Proceedings of the NATO Advanced workshop "New Methods for the Study of Molecular Aggregates", (Standing, K. and Ens, W., Eds.), pp. 239-276. Kluwer Academic Publishers, Dordrecht, Niederlande

  29. Przybylski, M., Schnaible, V., Kast, J., Bühler, S., Michels, J., Wattenberg, A., Fligge, T.A., Forst, D., Diederichs, K., Nestel, U., Zeth, K., Glocker, M.O., Welte,W. (1998)
    30. Approaches to the characterization of tertiary and supramolecular protein structures by combination of protein chemistry and mass spectrometry.
    In: Proceedings of the NATO Advanced workshop "New Methods for the Study of Molecular Aggregates", (Standing, K. and Ens, W., Eds.), pp. 17-43. Kluwer Academic Publishers, Dordrecht, Niederlande

  30. Forst, D., Welte, W., Wacker,T., Diederichs, K. (1998)
    31. Structure of ScrY, the sucrose-specific porin from Salmonella typhimurium, and its complex with sucrose.
    Nature Structural Biology 4, 34-45

  31. Diederichs, K., Freigang, J., Umhau, S., Zeth, K., Breed, J. (1998)
    32. Prediction by a Neural Network of Outer Membrane ß-strand Protein Topology.
    Protein Science 7, 2413-2420

  32. Ferguson, A., Breed, J., Welte, W., Diederichs, K., Coulton, J.W. (1998)
    33. An internal affinity-tag for purification and crystallization of the siderophore receptor FhuA, integral outer membrane protein from Escherichia coli K-12.
    Protein Science 7, 1636-1638

  33. Hars, U., Horlacher, R., Boos, W., Welte, W., Diederichs, K. (1998)
    34. Crystal Structure of the Effector-binding domain of the Trehalose-Repressor of Escherichia coli, a member of the LacI-family, in its Complexes with Inducer Trehalose-6-Phosphate and Non-Inducer Trehalose.
    Protein Science 7, 2511-2521

  34. Ferguson, A., Hofmann, E., Coulton, J.W., Diederichs, K., Welte, W. (1998)
    35. Siderophore-mediated iron transport: Crystal structure of FhuA with bound lipopolysaccharide.
    Science 282, 2215-2220

    1999

  35. Ritter, S., Diederichs, K., Frey, I., Berg, A., Keul, J., Baumstark, M. (1999)
    36. Crystallization of human low density lipoprotein - a large lipid-protein complex - collection of X-ray data at very low resolution.
    J. Cryst. Growth 196, 344-349

  36. Schwarzenbacher, R., Zeth, K., Diederichs, K., Gries, A., Kostner, G.M., Laggner, P., Prassl, R. (1999)
    37. Crystal structure of human ß2-glykoprotein I: implications for phospholipid binding and the antiphospholipid syndrome.
    EMBO J.18, 6228-6239

  37. Umhau, S., Diederichs, K., Welte, W., Ghisla, S., Pollegioni, L., Molla, G., Porrini, D., Pilone, M.S. (1999)
    38. Very high resolution crystal structure of D-amino acid oxidase. Insights into the reaction mechanism and mode of ligand binding.
    In: Flavins and Flavoproteins 1999, Proceedings of the thirteenth international symposium Konstanz, Germany, August 29 - September 4, 1999. Pp 567-570. Ghisla, S., Kroneck, P., Macheoux, P., Sund, H. (eds.). Rudolf Weber, Berlin 1999.

  38. Ritter, S., Hiller, R.G., Wrench, P.M., Welte, W., Diederichs, K. (1999)
    39. Crystal Structure of a phycourobilin-containing phycoerythrin at 1.90 Å resolution.
    J. Struct. Biol. 126, 86-97

    2000

  39. Kleima, F.J., Hofmann, E., Gobets, B.,van Stokkum, I.H.M., van Grondelle, R., Diederichs, K., van Amerongen, H. (2000)
    40. Förster Excitation Energy Transfer in Peridinin-Chlorophyll-a Protein.
    Biophys. J. 78, 344-353

  40. Freigang, J., Proba, K., Leder, L., Diederichs, K., Sonderegger, P., Welte, W. (2000)
    41. The crystal structure of the ligand-binding module of axonin-1/TAG-1 suggests a zipper-mechanism for neural cell adhesion.
    Cell 101, 425-433

  41. Ferguson, A.D., Braun, V., Fiedler, H.-P., Coulton, J.W., Diederichs, K., Welte, W. (2000)
    42. Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA.
    Protein Science 9, 956-963

  42. Ferguson, A.D., Welte, W., Hofmann, E., Lindner, B., Holst, O., Coulton, J.W., Diederichs, K. (2000)
    43. A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins.
    Structure 8, 585-592

  43. Diederichs, K. (2000)
    44. Computing in macromolecular crystallography using a parallel architecture.
    J. Appl. Cryst. 33, 1154-1161

  44. Ferguson, A.D., Coulton, J.W., Diederichs, K., Welte, W. (2000)
    45. The ferric hydroxamate uptake receptor FhuA and related TonB-dependant transporters in the outer membrane of gram-negative bacteria.
    Handbook of Metalloproteins (Wieghardt, K., Huber, R., Poulos, T.L., Messerschmidt, A., eds.) J. Wiley & Sons, Chichester, UK.

  45. Zeth, K., Diederichs, K., Welte, W., Engelhardt, H. (2000)
    46. Crystal structure of Omp32, the anion-selective porin from Comamonas acidovorans, in complex with a periplasmatic peptide at 2.1 Å resolution.
    Structure 8, 981-992

  46. Umhau, S., Pollegioni, L., Molla, G., Diederichs, K., Welte, W., Pilone, M.S., Ghisla, S. (2000)
    47. The X-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogentation.
    Proceedings of the National Academy of Sciences (USA) 97, 12463-12468.

  47. Diederichs, K., Diez, J., Greller, G., Müller, C., Breed, J., Schnell, C., Vonrhein, C., Boos, W., Welte, W. (2000)
    48. Crystal Structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archeon Thermococcus litoralis.
    EMBO J. 19, 5951-5961.

    2001

  48. Lunin, V.Y., Lunina, N.L., Ritter, S., Frey, I., Berg, A., Diederichs, K., Podjarny, A.D., Urzhumtsev, A., Baumstark, M.W. (2001)
    49. Low Resolution Data Analysis for Low Density Lipoprotein Particle.
    Acta Cryst D57, 108-121

  49. Umhau, S., Fritz, G., Diederichs, K., Breed, J., Welte, W., Kroneck, P.M.H. (2001)
    50. The three-dimensional structure of the nonaheme cytochrome c from Desulfovibrio desulfuricans Essex in the Fe(III) state at 1.89 Å resolution.
    Biochemistry 40, 1308-1316

  50. Diez, J., Diederichs, K., Greller, G., Horlacher, R., Boos, W., Welte, W. (2001)
    51. The Crystal Structure of a Liganded Trehalose/Maltose-Binding Protein from the Hyperthermophilic Archaeon Thermococcus litoralis at 1.85 Å.
    J. Mol. Biol. 305, 905-915

  51. Diederichs, K. (2001)
    52. Structure of the Outer Membrane Protein FhuA presents a Binding Mode for Lipopolysaccharide.
    Nova Acta Leopoldina Supplementum Nr. 16, 33-34

  52. Ferguson, A.D., Ködding, J., Walker, G., Bös, C., Coulton, J.W., Diederichs, K., Braun, V., Welte, W. (2001)
    53. Active Transport of an Antibiotic Rifamycin Derivative by the Outer Membrane Protein FhuA.
    Structure 9, 707-716

    2002

  53. Müller, S., Diederichs, K., Breed, J., Kissmehl, R., Hauser, K., Plattner, H., Welte, W. (2002)
    54. Crystal Structure Analysis of the Exocytosis-Sensitive Phosphoprotein, pp63/parafusin (Phosphoglucomutase), from Paramecium Reveals Significant Conformational Variability.
    J. Mol. Biol. 315, 141-153

  54. Freigang, J., Diederichs, K., Schäfer, K.P., Welte, W., Paul, R. (2002)
    55. Crystal structure of oxidized flavodoxin, an essential protein in Helicobacter pylori.
    Protein Science 11, 253-261

  55. Böhm, A., Diez, J., Diederichs, K., Welte, W., Boos, W. (2002)
    56. Structural Model of MalK, the ABC subunit of the maltose transporter of Escherischia coli: Implications for mal gene regulation, inducer exclusion and subunit assembly.
    J. Biol. Chem. 277, 3708-3717

  56. Pos, K.M., Diederichs, K. (2002)
    57. Purification, crystallization and preliminary diffraction studies of AcrB, an inner-membrane multi-drug efflux protein.
    Acta Cryst D58, 1865-1867

  57. Schiefner, A., Diederichs, K., Hashimoto, K., Boos, W., Welte, W. (2002)
    58. Crystallization and preliminary X-ray analysis of the trehalose/maltose ABC transporter MalFGK2 from Thermococcus litoralis.
    Acta Cryst D58, 2147-2149

  58. Pollegioni, L., Diederichs, K., Molla, G., Umhau, S.,  Welte, W., Ghisla, S., Pilone, M.S. (2002)
    59. Yeast D-amino acid oxidase: structural basis of it catalytic properties.
    J. Mol. Biol. 324, 535-546

    2003

  59. Soroka, V., Kolkova,  K., Kastrup, J.S., Diederichs, K., Breed, J., Poulsen, F.M. Larsen, I.K., Welte, W., Berezin, V., Bock, E., Kasper, C. (2003)
    60. Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion.
    Structure 11, 1291-1301

  60. Diederichs, K., McSweeney, S., Ravelli, R. (2003)
    61. Zero-dose extrapolation as part of macromolecular synchrotron data reduction.
    Acta Cryst D59, 903-909

    2004

  61. Schiefner, A., Breed, J., Bosser, L., Kneip, S., Gade, J., Holtmann, G., Diederichs, K., Welte, W., Bremer, E.  (2004)
    62. Cation-pi interactions as determinants for binding of the compatible solutes glycine betaine and proline betaine by the periplasmic ligand-binding protein ProX from Escherichia coli.
    J. Biol. Chem. 279, 5588-5596

  62. Schäfer, K., Magnusson, U., Scheffel, F., Schiefner, A., Sandgren, M.O., Diederichs, K., Welte, W., Hülsmann, A., Schneider, E., Mowbray, S.L. (2004)
    63. X-ray Structures of the Maltose-Maltodextrin-binding Protein of the Thermoacidophilic Bacterium Alicyclobacillus acidocaldarius Provide Insight into Acid Stability of Proteins.
    J. Mol. Biol. 335, 261-274

  63. Weiss MS, Mander G, Hedderich R, Diederichs, K., Ermler U, Warkentin E. (2004)
    64. Determination of a novel structure by a combination of long-wavelength sulfur phasing and radiation-damage-induced phasing.
    Acta Cryst D60, 686-695

  64. Mörtl, M., Diederichs, K., Welte, W., Molla, G., Motteran, L., Andriolo, G., Pilone, M.S., Pollegioni, L. (2004)
    65. Structure-function correlation in glycine oxidase from Bacillus subtilis.
    J. Biol. Chem. 279, 29718-29727

  65. Pos, K.M., Schiefner, A., Seeger, M.A., Diederichs, K. (2004)
    66. Crystallographic analysis of AcrB.
    FEBS Lett. 564, 333-339

  66. Ködding, J., Polzer, P., Killig, F., Howard, S.P., Gerber, K., Seige, P., Diederichs, K., Welte, W. (2004)
    67. Crystallization and preliminary X-ray analysis of a C-terminal TonB fragment from Escherichia coli.
    Acta Cryst D60, 1281-1283

  67. Schiefner, A., Holtmann, G., Diederichs, K., Welte, W., Bremer, E. (2004)
    68. Structural basis for the binding of compatible solutes by ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus.
    J Biol Chem. 279, 48270-48281

  68. Köhler, R., Schäfer, K., Müller, S., Vignon, G., Diederichs, K., Philippsen, A., Ringler, P., Pugsley, A.P., Engel, A., Welte, W. (2004)
    69. Structure and assembly of the pseudopilin PulG.
    Mol. Microbiol. 54, 647-664

    2005

  69. Ködding, J., Killig, F., Polzer, P., Howard, S.P., Diederichs, K., Welte, W. (2005)
    70. Crystal structure of a 92-residue c-terminal fragment of TonB from Escherichia coli reveals significant conformational changes compared to structures of smaller TonB fragments.
    J Biol Chem. 280, 3022-3028

  70. Weissenborn, R., Diederichs, K., Welte, W., Maret, G., Gisler, T. (2005)
    71. Non-thermal microwave effects on protein dynamics? An X-ray diffraction study on tetragonal lysozyme crystals.
    Acta Cryst D61, 163-172

  71. Meier, T., Polzer, P., Diederichs, K., Welte, W., Dimroth, P. (2005)
    72. Structure of the Rotor Ring of F-Type Na+-ATPase from Ilyobacter tartaricus.
    Science 308, 659-662
    Supporting Online Material

  72. Schiefner A., Gerber K., Seitz S., Welte W., Diederichs, K., Boos W. (2005)
    73. The crystal structure of Mlc, a global regulator of sugar metabolism in Escherichia coli..
    J Biol Chem. 280, 29073-9

    2006

  73. Diederichs, K. (2006)
    74. Some aspects of quantitative analysis and correction of radiation damage.
    Acta Cryst D62, 96-101

  74. Krug, M., Lee, SJ., Diederichs, K., Boos, W., Welte, W. (2006)
    75. Crystal structure of the sugar binding domain of the archaeal transcriptional regulator TrmB..
    J Biol Chem. 281, 10976-82

  75. Seeger, M.A., Schiefner, A., Eicher, T., Verrey, F., Diederichs, K., Pos, K.M. (2006)
    76. Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.
    Science 313, 1295-1298
    Supporting Online Material

    2007

  76. Mörtl, M., Sonderegger, P., Diederichs, K., Welte, W. (2007)
    77. The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction.
    Protein Sci. 16(10), 2174-2183.

  77. Diederichs, K., Pos, K.M. (2007)
    78. Peristaltischer Antibiotika-Transport durch ein Multidrug-Resistenzprotein.
    Biospektrum 7, 721-723

    2008

  78. Seeger, M.A., Ballmoos, C.v., Eicher, T., Brandstätter, L., Verrey, F., Diederichs, K., Pos, K.M. (2008)
    79. Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB.
    Nature Struct. Mol. Biol. 15(2), 199-205
    Supporting Online Material

  79. Vorburger, T., Zingg Ebneter, J., Wiedenmann, A., Morger, D., Weber, G., Diederichs, K., Dimroth, P., von Ballmoss, C. (2008)
    80. Arginine-induced conformational change in the c-ring/a-subunit interface of ATP synthase.
    FEBS J. 275, 2137-50

  80. Nesper, J., Brosig, A., Ringler, P., Patel, G.J., Müller, S.A., Kleinschmidt, J.H., Boos, W., Diederichs, K., Welte, W. (2008)
    81. Omp85(Tt) from Thermus thermophilus HB27: an ancestral type of the Omp85 protein family.
    J Bacteriol. 190(13),4568-75

  81. Schiffer, A., Parey, K., Warkentin, E., Diederichs, K., Huber, H., Stetter, K.O., Kroneck, P.M., Ermler, U. (2008)
    82. Structure of the dissimilatory sulfite reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus.
    J Mol Biol. 379(5), 1063-74

  82. Brosig, A., Nesper, J., Welte, W., Diederichs, K. (2008)
    83. Expression, crystallization and preliminary X-ray analysis of an outer membrane protein from Thermus thermophilus HB27.
    Acta Cryst. F64(Pt 6), 533-36

  83. Brosig, A., Nesper, J., Boos, W., Welte, W., Diederichs, K. (2008)
    84. Crystal Structure of a Major Outer Membrane Protein from Thermus thermophilus HB27.
    J. Mol. Biol. 385(5), 1445-55

  84. Seeger, M.A., Diederichs, K., Eicher, T., Brandstätter, L., Schiefner, A., Verrey, F., Pos, K.M. (2008)
    85. The AcrB Efflux Pump: Conformational Cycling and Peristalsis Lead to Multidrug Resistance.
    Current Drug Targets 9, 729-49

    2009

  85. Diederichs, K., Junk, M. (2009)
    86. Post-processing intensity measurements at favourable dose values.
    J. Appl. Cryst. 42, 48-57

  86. Krieg, S., Huché, F., Diederichs, K., Izadi-Pruneyre, N., Lecroisey, A., Wandersman, C., Delepelaire, P., Welte, W. (2009)
    87. Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex.
    Proc. Natl. Acad. Sci. U S A. 106, 1045-50
    Supporting Online Material

  87. Meier, T., Krah, A., Bond, P. J., Pogoryelov, D., Diederichs. K., Faraldo-Gómez, J. D. (2009)
    88. Complete ion-coordination structure in the rotor ring of Na(+)-dependent F-ATP synthases.
    J. Mol. Biol. 391, 498-507

  88. Diederichs K. (2009)
    89. Simulation of X-ray frames from macromolecular crystals using a ray-tracing approach.
    Acta Cryst. D65, 535-42

    2010

  89. Faust, A., Puehringer, S., Darowski, N., Panjikar, S., Diederichs, K., Mueller, U., Weiss, M. S. (2010)
    90. Update on the tutorial for learning and teaching macromolecular crystallography.
    J. Appl. Cryst. 43, 1230-7

  90. Obeid, S., Blatter, N., Kranaster, R., Schnur, A., Diederichs, K., Welte, W., Marx, A. (2010)
    91. Replication through an abasic DNA lesion: structural basis for adenine selectivity.
    EMBO J. 29, 1738-47

  91. Piontek, K., Ullrich, R., Liers, C., Diederichs, K., Plattner, D. A., Hofrichter, M. (2010)
    92. Crystallization of a 45 kDa peroxygenase/peroxidase from the mushroom Agrocybe aegerita and structure determination by SAD utilizing only the haem iron.
    Acta Cryst. F 66, 693-8

  92. Diederichs, K. (2010)
    93. Quantifying instrument errors in macromolecular X-ray data sets.
    Acta Cryst. D 66, 733-40

  93. Schwefel, D., Maierhofer, C., Beck, J. G., Seeberger, S., Diederichs, K., Möller, H. M., Welte, W., Wittmann, V. (2010)
    94. Structural basis of multivalent binding to wheat germ agglutinin.
    J. Am. Chem. Soc. 132, 8704-19

  94. Betz, K., Streckenbach, F., Schnur, A., Exner, T., Welte, W., Diederichs, K., Marx, A. (2010)
    95. Structures of DNA Polymerases Caught Processing Size-Augmented Nucleotide Probes.
    Angew. Chem. Int. Ed. Engl. 49, 5181-84
    Supporting Online Material

  95. Litzinger, S., Fischer, S., Polzer, P., Diederichs, K., Welte, W., Mayer C. (2010)
    96. Structural and Kinetic Analysis of Bacillus subtilis N-Acetylglucosaminidase Reveals a Unique Asp-His Dyad Mechanism.
    J Biol Chem. 285(46), 35675-84

  96. Obeid, S., Baccaro, A., Welte, W., Diederichs, K., Marx, A. (2010)
    97. Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase.
    Proc Natl Acad Sci U S A 107, 21327-31
    Supporting Online Material

    2011

  97. Domingo Köhler, S., Spitzbarth, M., Diederichs, K., Exner, T.E., Drescher, M. (2011)
    98. A short note on the analysis of distance measurements by electron paramagnetic resonance.
    J Magn Reson. 208(1), 167-70

  98. Gieseking, S., Bergen, K., Di Pasquale, F., Diederichs, K., Welte, W., Marx, A. (2011)
    99. Human DNA polymerase β mutations allowing efficient abasic site bypass.
    J Biol Chem. 286, 4011-20

  99. Obeid, S., Schnur, A., Gloeckner, C., Blatter, N., Welte, W., Diederichs, K., Marx, A. (2011)
    100. Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity.
    Chembiochem. 12, 1574-80

  100. Grädler, U., Fuchß, T., Ulrich, W.R., Boer, R., Strub, A., Hesslinger, C., Anézo, C., Diederichs, K., Zaliani, A. (2011)
    101. Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights.
    Bioorg Med Chem Lett. 21, 4228-32

    2012

  101. Eicher, T., Cha, H.J., Seeger, M.A., Brandstätter, L., El-Delik, J., Bohnert, J.A., Kern, W.V., Verrey, F., Grütter, M.G., Diederichs, K., Pos, K.M. (2012)
    102. Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.
    Proc Natl Acad Sci U S A 109(15), 5687-92
    Supporting Online Material

  102. Bergen, K., Steck, A.L., Strütt, S., Baccaro, A., Welte, W., Diederichs, K., Marx, A. (2012)
    103. Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates.
    J Am Chem Soc. 134(29), 11840-3
    Supporting Online Material

  103. Obeid, S., Welte, W., Diederichs, K., Marx, A. (2012)
    104. Amino acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase.
    J Biol Chem. 287(17), 14099-108
    Supporting Online Material

  104. Karplus P.A., Diederichs, K. (2012)
    105. Linking crystallographic model and data quality.
    Science 336(6084), 1030-3
    Supporting Online Material

  105. Betz, K., Malyshev, D.A., Lavergne, T., Welte, W., Diederichs, K., Dwyer, T.J., Ordoukhanian, P., Romesberg, F.E., Marx, A. (2012)
    106. KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.
    Nat Chem Biol. 8(7), 612-14
    Supporting Online Material

  106. Holzberger, B., Obeid, S., Welte, W., Diederichs, K., Marx, A. (2012)
    107. Structural insights into the potential of 4-fluoroproline to modulate biophysical properties of proteins.
    Chemical Science 3, 2924-2931
    Supporting Online Material

  107. Obeid, S., Bußkamp, H., Welte, W., Diederichs, K., Marx A. (2012)
    108. Interactions of non-polar and "Click-able" nucleotides in the confines of a DNA polymerase active site.
    Chem Commun (Camb.) 48(67), 8320-2
    Supporting Online Material

  108. Eibl, C., Grigoriu, S., Hessenberger, M., Wenger, J., Puehringer, S., Pinheiro, A.S., Wagner, R.N., Proell, M., Reed, J.C., Page, R., Diederichs, K., Peti, W. (2012)
    109. Structural and functional analysis of the NLRP4 pyrin domain.
    Biochemistry 51(37), 7330-41
    Supporting Online Material

    2013

  109. Grimm, C., Chari, A., Pelz, J.P., Kuper, J., Kisker, C., Diederichs, K., Stark, H., Schindelin, H., Fischer, U. (2012)
    110. Structural Basis of Assembly Chaperone- Mediated snRNP Formation.
    Mol Cell [Epub ahead of print]
    Supporting Online Material
Abstracts? - please obtain a PubMed listing of the papers