Protein Crystallography and Molecular Bioinformatics
University of Konstanz

Recent Publications

 

"Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity "

Samra Obeid, Andreas Schnur, Christian Gloekner, Nina Blatter, Wolfram Welte, Kay Diederichs and Andreas Marx

ChemBioChem Vol. 12 pp. 1574-1580 (2011)


Figure legend:
Interaction network of incoming ddATP oposite abasic site in crystal structures of a KlenTaq double mutant (sand and grey) compared with KlenTaq wildtype (purple and cyan).

Link to ChemBioChem:
Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity



"Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex"

Krieg, S., Huché, F., Diederichs, K., Izadi-Pruneyre, N., Lecroisey, A., Wandersman, C., Delepelaire, P., Welte, W.

Proc. Nat. Acad. Sci. Vol. 106 pp. 1045-1050 (2009)

  [Keine Beschreibung eingegeben]

Link to PNAS:
Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex.



"Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB"

Seeger, M.A., Ballmoos, C.v., Eicher, T., Brandstätter, L., Verrey, F., Diederichs, K., Pos, K.M.

Nature Struct. Mol. Biol. Vol. 15(2) pp. 199-205 (2008)

  [Keine Beschreibung eingegeben]

Link to pdf:
Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB